The effect of high positive end expiratory pressure and low tidal volume on oxygenation during robot-assisted partial nephrectomy

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038103

Enrollment

Unknown

Registered

2020-09-10

Start date

2020-09-15

Completion date

Unknown

Last updated

2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary tumor

Interventions

High positive end expiratory pressure:ventilated with 12cm H2O peep in the operation

Traditional positive end expiratory pressure:ventilated with 4cm H2O peep in the operation

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiology physical status I or II; 2. Patients aged 18 to 65 years male or female; 3. Scheduled for Robot-assisted partial nephrectomy.

Exclusion criteria

Exclusion criteria: 1. Impaired lung function (chronic obstructive pulmonary disease grade greater than 3 or forced expiratory volume in 1s less than 1000ml); 2. Chronic heart failure(cardiac index less than 1.8L/m2); 3. BMI>40kg/m2; 4. Previous lung surgery.

Design outcomes

Primary

Measure	Time frame
PaO2/FiO2 ratio;	—

Secondary

Measure	Time frame
respiratory mechanics parameters;hemodynamics parameters;blood gas analysis;pulmonary complications;	—

Countries

China

Contacts

Public ContactWei Li

Sun Yet-Sen University Cancer Center

Liw@sysucc.org.cn+86 13602855006

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026