Sufentanil injection in epidural prevents sufentanil-induced cough

Sufentanil injection in epidural prevents sufentani-induced cough

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000038090

Enrollment

Unknown

Registered

2020-09-10

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sufentanil-induced cough

Interventions

A:5 ml saline was given to epidural

B:5 ml sufentanil 0.75ug/ml was given to epidural

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: ASA grade I or II, aged 20-70, undergoing elective surgery under general anesthesia with epidural anesthesia.

Exclusion criteria

Exclusion criteria: Patients with BMI greater than 28; patients with increased intracranial pressure, intraocular pressure and intra-abdominal pressure; patients with respiratory system diseases, such as asthma, chronic cough, upper respiratory tract infection within two weeks; other systemic diseases, such as gastroesophageal reflux, heart disease, liver and kidney dysfunction; patients with long-term opioid use history, and patients who have used ACEI, antitussive drugs, bronchodilators and hormones.

Design outcomes

Primary

Measure	Time frame
count of cough;	—

Countries

China

Contacts

Public ContactYunchang Mo

The First Affiliated Hospital of Wenzhou Medical University

85670312@qq.com+86 13736924260

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026