Patients under mechanical ventilation in ICU
Conditions
Interventions
Sponsors
The Third Affiliated Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 18 years of age or older; 2. Need for mechanical ventilation for at least 24 hours; 3. Have concurrent invasive arterial blood pressure monitoring, and require sputum suction under mechanical ventilation.
Exclusion criteria
Exclusion criteria: 1. Long-term use of opioids, benzodiazepines, non-benzodiazepines and other analgesic sedatives for more than 3 months or allergies; 2. Unstable hemodynamics; 3. During pregnancy or lactation; 4. Severe brain injury, high spinal cord injury, brain death, and use of muscle relaxants; 5. Chromocytoma and other patients with adrenal medulla; 6. Those who take monoamine oxidase inhibitors; 7. Participating in other drug research or clinical trials; 8. Fail to obtain informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hemodynamic changes before and after sputum suction; | — |
Secondary
| Measure | Time frame |
|---|---|
| CPOT score before and after sputum suction;Coughing score before and after suction;Catecholamine levels; | — |
Countries
China
Contacts
Public ContactHong Yang
The Third Affiliated Hospital of Southern Medical University
Outcome results
None listed