Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Hypertensive patients, age 65yr-70yr, gender is not limited; in the case of not using antihypertensive drugs, blood pressure was measured 3 times on different days, systolic blood pressure >= 140mmHg and (or) diastolic blood pressure >= 90mmHg or a clear diagnosis of hypertension Elderly people who are being treated with antihypertensive drugs should still be included in the group even if their blood pressure is < 140/90mmHg. 2. Patients receiving routine gastroscopy diagnosis and treatment; 3. The ASA score is level II and level III; 4. 18 kg/m2 < BMI < 30kg/m2 5. It is estimated that the operation time of gastroscope will not exceed 30 minutes; 6. Clearly understand, participate in the research voluntarily, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Complicated endoscopic diagnosis and treatment techniques (such as cholangiopancreatography, endoscopic ultrasound, endoscopic mucosal resection, endoscopic submucosal dissection, oral endoscopic muscle dissection, etc.) are required; 2. Patients who intend to undergo tracheal intubation; 3. Patients who are judged to be difficult to manage the respiratory tract (modified Markov score is grade IV); 4. Anemia or thrombocytopenia, Hb = 2.5 x ULN, TBIL >= 1.5 x ULN; 6. Abnormal renal function, blood creatinine is greater than the upper limit of normal; 7. There is a history of drug abuse and/or alcohol abuse within 2 years before the beginning of the screening period, alcohol abuse means that the average daily alcohol consumption exceeds 2 units of alcohol (1 unit = 360 mL of beer or 45 mL of 40% alcoholic liquor or 150 mL of wine); 8. Sitting systolic blood pressure <= 90 mmHg during the screening period; 9. Women who are pregnant or breastfeeding; 10. Those who are allergic or contraindicated to benzodiazepines, opioids, propofol, lidocaine and their drug components; 11. Participated in drug clinical trials as subjects in the past 3 months; 12. The investigator believes that it is inappropriate to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| blood pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart beats;Pulse oxygen saturation;Recovery time; | — |
Countries
China
Contacts
Liaocheng People's Hospital