Diseases of the upper digestive tract requiring endoscopy
Conditions
Interventions
Moderate sandation:Midazolam combined with fentanyl
Deep sedation:Midazolam combined with fentanyl
Sponsors
Shangluo Central Hospital
Eligibility
Sex/Gender
All
Age
19 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged >= 18 years, regardless of gender; 2. The American society of anesthesiologists (ASA) I - II level; 3. Patients with indications and selected EGD in our hospital; 4. Subjects participate voluntarily and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications of routine endoscopic operations or patients who refused to be sedate; 2. Patients with uncontrolled circulatory and respiratory diseases that may threaten their lives, such as uncontrolled severe hypertension, severe arrhythmia, unstable angina, acute respiratory infection and asthma attack period; 3. Patients with other severe cardiopulmonary diseases; 4. Patients with liver dysfunction (child-Pugh grade C or above), acute upper gastrointestinal bleeding with shock, severe anemia, gastrointestinal obstruction with gastric content retention; 5. Risk of allergy to sedatives and analgesics and other severe anesthesia; 6. Addicts of long-term use of sedative and analgesic drugs or alcohol or sedative and analgesic drugs; 7. Pregnant and lactating women; 8. Without escort or guardian; 9. Other conditions in which the researcher considers it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depth of sedation;Hemodynamics and oxygen metabolism;Adverse events; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation time; | — |
Countries
China
Contacts
Public ContactLiu Xiao
Shangluo Central Hospital
Outcome results
None listed