Cerebral infarction
Conditions
Interventions
Research two Experimental group A:rTMS, Conventional drug treatment and rehabilitation treatment
Research two Experimental group B:rTMS, Conventional drug treatment and rehabilitation treatment
Sponsors
Jiangsu Provincial Hospital
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for cerebral infarction in the Cerebrovascular Disease developed by the fourth National Academic Conference on cerebrovascular Disease in 1995; (2) Primary or unilateral onset or previous onset without residual neurological dysfunction; (3) Stable vital signs and clear consciousness; (4) 40 ~ 70 years old; (5) Course of disease 1 week to 3 month; (6) Paralysis of the upper limbs; (7) Fugl-meyer point <= 22 after onset; (9) The informed consent is signed by the candidate himself or his family members.
Exclusion criteria
Exclusion criteria: (1) A history of epilepsy, a history of idiopathic epilepsy in a first-degree relative, and the use of epileptogenic drugs; (2) The function of heart, lung, liver, kidney and other important organs decreases or fails; (3) Severe cognitive and communication impairment and inability to cooperate; (4) Posterior circulation infarction; (5) Wearing a pacemaker, having a metal implant in the skull, or having skull defects; (6) Severe cervical spondylosis includes severe cervical stenosis and cervical instability; (7) Complete occlusion of the internal carotid artery; (8) Direct injuries and skull defects in the stimulation area; (9) women during pregnancy; (10) Implant artificial metal heart valve, insulin pump, drug therapy pump, aneurysm clip (other than titanium alloy, which is not paramagnetic) in the body; (11) There are metal implants in the body, such as metal prosthesis and other ferromagnetic foreign bodies (12) Patients with severe high fever; (13) Patients with claustrophobia; (14) fMRI examination of uncooperative patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-meyer motor function evaluation of upper limbs;Hong Kong edition of functional test for the hemiplegic upper extremity, FTHUE-HK;motor threshold, MT;Cortical latency of MEP;central motor conduction time, CMCT; | — |
Secondary
| Measure | Time frame |
|---|---|
| sum of the shoulder abduction and finger extension medical research council muscle grades, SAFE;NIHSS;Motricity index, MI;Modified Barthel index;Modified Ashworth scale;fractional anisotropy asymmetry index, FAAI; | — |
Countries
China
Contacts
Public ContactWang Tong
Jiangsu Province Hospital
Outcome results
None listed