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The Implication of ctDNA in the Recurrence Surveillance of Liver Transplantation for Hepatocellular Carcinoma

The Implication of ctDNA in the Recurrence Surveillance of Liver Transplantation for Hepatocellular Carcinoma

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037998
Enrollment
Unknown
Registered
2020-09-08
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Transplantation for Hepatocellular Carcinoma

Interventions

Gold Standard:Clinical outcome

Sponsors

The First Affiliated Hospital of Medical College, Xi'an Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: (1) The age of the recipient is 18-70 years old. Primary liver cancer was diagnosed by medical history, imaging and postoperative pathology. No tumor metastasis and no other tumors. No treatment within two months before transplantation; (2) Organ donation is China III-type, which meet the reasonable donation process. No general organ donation absolute contraindications; (3) Donor recipient family or legal representative agrees to participate in this trial and signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Recipients have other tumors or signs of extrahepatic metastasis; (2) Recipients received treatment within 2 months before surgery, including but not limited to radiofrequency ablation (RFA), percutaneous alcohol ablation (PEA); (3) Conditions considered unsuitable for inclusion by researchers.

Design outcomes

Primary

MeasureTime frame
RFS;SEN, SPE, ACC, AUC of ROC;

Countries

China

Contacts

Public ContactRuitao Wang

The First Affiliated Hospital of Medical College, Xi’an Jiaotong University

wruitao2008@126.com+86 18966724007

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026