Laparoscopic hysterectomy
Conditions
Interventions
Group C:Norm saline
Group EP:Esketamine combined with parecoxib
Sponsors
Wuxi Xishan People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. The patients who underwent laparoscopic hysterectomy were selected; 2. Patients aged 18-65 years old; 3. Patients with body mass index of 15-30 kg / m2; 4. Patients with preoperative American Society of anesthesiologists (ASA) grade I ~ II.
Exclusion criteria
Exclusion criteria: 1. Patients with severe heart and lung diseases; 2. Patients with liver and kidney dysfunction; 3. Patients with chronic pain history; 4. Patients with mental illness; 5. Patients with a history of gastrointestinal disease (peptic ulcer disease, Crohn's disease or ulcerative colitis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mechanical hyperalgesia threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxycodone consumption for first 48 h postoperatively;NRS scores at different time after surgery;Postoperative adverse effects; | — |
Countries
China
Contacts
Public ContactQingren Liu
Wuxi Xishan People's Hospital
Outcome results
None listed