Breast cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with age >= 18 years old; 2. Patients with brain metastatic breast cancer confirmed by histology or cytology (HER-2 expression positive refers to the patients with no less than 10% tumor cells with immunohistochemical staining intensity of 2 + and confirmed by fluorescence in situ hybridization [fish], or immunohistochemical staining intensity of 3 + [color intensity range 0-3]); 3. The decision-making plan of clinicians includes pyrrolidine; 4. Patients whose clinical data can be traced.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating women; 2. Patients who could not understand the study or failed to sign the informed consent form; 3. Patients without follow-up data; 4. Other patients who are not suitable for the study;
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Overall Survival;Objective Response Rate;Duration of Response;Clinical Benefit Rate;Quality of Life;Compliance; | — |
Primary
| Measure | Time frame |
|---|---|
| Progression Free Survival;Adverse Events; | — |
Countries
China
Contacts
Shandong Cancer Hospital and Institute