Elective cesarean section
Conditions
Interventions
eligible non scarred uterus group:Oxytocin infusion, oxytocin bolus, myometrium oxytocin receptor and a-SMA receptor on immunohistochemical analysis, isometric tension test of myometrial strip
Senile non scarred uterus group:Oxytocin infusion, oxytocin bolus, myometrium oxytocin receptor and a-SMA receptor on immunohistochemical analysis, isometric tension test of myometrial strip
eligible scarred uterus group:Oxytocin infusion, oxytocin bolus, myometrium oxytocin receptor and a-SMA receptor on immunohistochemical analysis, isometric tension test of myometrial strip
Senile scarred uterus group:Oxytocin infusion, oxytocin bolus, myometrium oxytocin receptor and a-SMA receptor on immunohistochemical analysis, isometric tension test of myometrial strip
Sponsors
Jiaxing University Affiliated women and children Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Objects of ASA I - II; 2. Subjects aged 18-50 years; 3. The subject of singleton pregnancy; 4. Subjects of non scar uterus, scar uterus; 5. Patients undergoing elective cesarean section; 6. The subject of abdominal transverse incision; 7. For patients with hemiplegia, the anesthesia plane is T4-T6.
Exclusion criteria
Exclusion criteria: 1. Pregnant women entering labor; 2. The subject of premature rupture of amnion; 3. Subjects allergic to oxytocin; 4. Patients with severe obstetric complications (gestational hypertension, preeclampsia); 5. Subjects of predicted high risk factors for postpartum hemorrhage (placental abnormalities, macrosomia, uterine fibroids, postpartum uterine atony and history of hemorrhagic disease); 6. Subjects with congenital and acquired coagulation dysfunction; 7. Subjects with thrombocytopenia (platelet count < 100 x 10 ^ 9).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxytocin dose;Estimate blood loss;Uterine constraction score;Side effects;Oxytocin effective dose in 50% of parturients (ED50) for adequate uterine tone;Oxytocin effective dose in 90% of parturients (ED90) for adequate uterine tone; | — |
Countries
China
Contacts
Public ContactChangna Wei
Jiaxing University Affiliated Women and Children Hospital
Outcome results
None listed