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The role of autophagy of BMSCs induced by oxidative stress in tendon bone healing

The role of autophagy of BMSCs induced by oxidative stress in tendon bone healing

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037969
Enrollment
Unknown
Registered
2020-09-08
Start date
2020-11-01
Completion date
Unknown
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rotator cuff Tear

Interventions

chronic rotator cuff injur group vs control group (male and femal)):Nil

Sponsors

The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who meet the diagnostic criteria of rotator cuff injury and have been injured for more than 6 weeks; 2. Patients aged 50-75 years; 3. Patients who voluntarily join and sign the informed agreement.

Exclusion criteria

Exclusion criteria: 1. Patients who meet the diagnostic criteria of rotator cuff injury and have been injured for more than 6 weeks; 2. Patients aged 50-75 years; 3. Patients who voluntarily join and sign the informed agreement.

Design outcomes

Primary

MeasureTime frame
Total reactive oxygen species in clinical samples;Superoxide in clinical samples;MRNA expression of Beclin1 and mTOR genes in sample tissues;Expression of Beclin1 and mTOR gene proteins in sample tissues;

Countries

China

Contacts

Public ContactZhijun Liu M.D.

The Third Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine

liuanson@126.com+86 18824188657

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026