Skip to content

A comparison of sugammadex and neostigmine to reverse neuromuscular blockade on postoperative pulmonary function and residual muscular effects in ERAS thoracic surgery

A comparison of sugammadex and neostigmine to reverse neuromuscular blockade on postoperative pulmonary function and residual muscular effects in ERAS thoracic surgery: a randomized, controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037964
Enrollment
Unknown
Registered
2020-09-07
Start date
2020-09-20
Completion date
Unknown
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pulmonary function

Interventions

Group 2:Rocuronium-Sugammadex
Group 1:Cisatracurium - neostigmine

Sponsors

Department of Anesthesiology, Shanghai Chest Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-65 years old; 2. Patients undergoing VATS assisted lung surgery under general anesthesia (single lobectomy) were transferred to PACU immediately after surgery; 3. Patients with normal pulmonary function before operation (FEV1 > 70% of the predicted value, diffusion greater than 70% of the predicted value); 4. Patients with operation time >=1 hour; 5. Subjects of informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with previous mental illness or patients taking psychotropic drugs due to epilepsy; 2. Patients with neuromuscular diseases (myasthenia gravis, progressive muscular dystrophy, periodic paralysis, congenital myopathy, hemiplegia, nervous system diseases, etc.); 3. Patients with mediastinal tumor; 4. With Severe cardio-cerebrovascular, liver, kidney and metabolic diseases; 5. Patients with poor pulmonary function, hypoxemia PaO2 50mmhg; 6. Patients with skin temperature less than 32 degrees C.

Design outcomes

Primary

MeasureTime frame
FEV1;

Countries

China

Contacts

Public ContactQimeng Yu

Shanghai Chest Hospital

fishyuye@163.com+86 13601664754

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026