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Relationship between dose and radiotherapy related hypothyroidism in patients with nasopharyngeal carcinoma — accurate dose distribution by AcurosXB calculation system

Relationship between dose and radiotherapy related hypothyroidism in patients with nasopharyngeal carcinoma — accurate dose distribution by AcurosXB calculation system

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037936
Enrollment
Unknown
Registered
2020-09-04
Start date
2020-05-05
Completion date
Unknown
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal carcinoma

Interventions

Sponsors

Affiliated Hospital of Panzhihua University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. The age of subjects = 18 years old is less than or equal to 75 years old; 2. Patients with nasopharyngeal carcinoma confirmed by histopathology; 3. Patients receiving initial treatment; 4. Patients with PS = 2; 5. Patients with an expected survival time of more than 6 months; 6. Patients who voluntarily sign informed consent form; 7. Patients with good compliance meet the follow-up conditions.

Exclusion criteria

Exclusion criteria: 1. Patients with previous history of head and neck radiotherapy; 2. Patients with diseases related to hypothalamus and pituitary gland; 3. Patients with primary endocrine diseases; 4. Patients with mental illness; 5. Patients with hormone replacement therapy; 6. Pregnant and lactating women; 7. Patients with ALB < 30g / L; 8. Patients with WBC < 4.0 × 10 ^ 9 / L, hemoglobin < 80 g / L, PLT < 50 × 10 ^ 9 / L; 9. Patients with high fever without control; 10. Patients with abnormal serum creatinine level 3 and 4; 11. Patients with grade 3 and 4 Abnormal alanine aminotransferase and glutamic oxalate value.

Design outcomes

Primary

MeasureTime frame
pituitary function;

Countries

China

Contacts

Public ContactLei Xiaolin

Affiliated Hospital of Panzhihua University

2428086827@qq.com+86 15892560358

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026