Salivary gland benign hypertrophy
Conditions
Interventions
The treatment group:Botulinum toxin A injection
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients over 18 years old; 2. Patients without basic diseases; 3. Patients with benign enlargement of salivary glands without obvious symptoms and without sialopathy.
Exclusion criteria
Exclusion criteria: 1. Patients with benign or malignant parotid / submandibular gland tumors; 2. Patients with parotid / submandibular gland skin infection or ulceration; Patients with allergy to botulinum toxin type A; 4. Patients with neuromuscular diseases, such as myasthenia gravis, Lambert Eaton syndrome, motor neuropathy or amyotrophic lateral sclerosis; 5. Patients receiving aminoglycoside antibiotics, penicillin, quinine or calcium channel blockers (can be used after withdrawal). 5. Patients with abnormal local anatomy; 6. Pregnant and lactating women; 7. Patients with severe heart, lung, liver and kidney diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parotid/submandibular volume;Facial standard photograph;Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The distance from screen front midpoint to mandibular Angle;The distance from the lower margin of mastoid process to the highest point of masseter muscle; | — |
Countries
China
Contacts
Public ContactLi Guangshuai
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed