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The role of gut microbiome in the progression of systemic inflammatory responses in acute aortic dissection

The role of gut microbiome in the progression of systemic inflammatory responses in acute aortic dissection

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037930
Enrollment
Unknown
Registered
2020-09-04
Start date
2020-09-04
Completion date
Unknown
Last updated
2020-11-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic dissection

Interventions

Case series:Nil

Sponsors

Department of Cardiovascular Surgery, West China Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The age of the patients ranged from 18 to 80 years old; 2. Patients with definite diagnosis of aortic aneurysm or aortic dissection; 3. Patients who have not received endovascular aortic repair and arterial replacement.

Exclusion criteria

Exclusion criteria: 1. Patients who have used antibiotics or probiotics within 3 months; 2. Patients who have undergone major gastrointestinal surgery (including gastrointestinal tract, cholecystectomy and appendectomy) within 5 years; 3. Patients with inflammatory bowel disease, including ulcerative colitis, Crohn's disease, etc; 4. Patients with irritable bowel syndrome; 5. Patients with chronic gastroenteritis, diarrhea of unknown origin and chronic constipation.

Design outcomes

Primary

MeasureTime frame
Species of intestinal bacteria;Number of intestinal bacteria;Metabolite species in serum;Metabolite concentrations in serum;

Countries

China

Contacts

Public ContactJia Hu

Department of Cardiovascular Surgery, West China Hospital, Sichuan University

1725194@qq.com+86 18682560211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026