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Application of psma-pet imaging in accurate diagnosis and treatment of prostate cancer

Clinical transformation of 18f-psma PET / MR imaging targeting prostate puncture with innovative molecular probe

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037919
Enrollment
Unknown
Registered
2020-09-04
Start date
2020-09-07
Completion date
Unknown
Last updated
2021-11-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostate cancer

Interventions

of&#32
prostate,&#32
Gleason
Gold Standard:Gold Standard: Pathology
Index test:PSMA/MR,&#32
the&#32

Sponsors

Chines PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 45-75 years; 2. Patients with PSA higher than normal for 3 consecutive months; 3. Patients with a PS score of 0 or 1 in ECoG; 4. Patients whose life expectancy is more than 10 years; 5. Patients who can cooperate with and tolerate psma-pet / MR examination; 6. Men who can tolerate and cooperate with prostate puncture and choose radical prostatectomy as the main treatment for prostate cancer after diagnosis; 7. Patients with normal bone marrow function: neutrophil count >= 1.5 x 10^9 / L; platelet count >= 100 x 10^9 / L; hemoglobin >= 90 g / L; white blood cell count >= 3.6 x 10^9 / L; 8. Patients with normal coagulation function: INR <= 1.5, APTT <=1.5 times ULN, Pt < ULN + 4 seconds; 9. The ability of the subjects to understand and be willing to sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with other known malignant tumors; 2. Patients with known HIV or AIDS related diseases, active or symptomatic viral hepatitis or chronic liver disease; 3. Patients with claustrophobia, etc., who can not tolerate psma-pet / MR examination during the course of treatment; 4. Patients who refuse or can't tolerate prostate puncture examination; 5. Patients who give up surgical treatment after diagnosis of prostate cancer.

Design outcomes

Primary

MeasureTime frame
SUV;DWI;prostate specific antigen, PSA;Gleason;

Secondary

MeasureTime frame
the location of the cancer;

Countries

China

Contacts

Public ContactXu Baixuan

Chines PLA General Hospital

xbx301@163.com+86 010-66936469

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026