Recombinant human collagen gel dressing was applied to the donor wound during skin grafting.
Conditions
Interventions
A:recombinant human collagen hydrogel
Sponsors
Department of Burns, First Affiliated Hospital of Naval Medical University (formerly Department of Burns, Shanghai Changhai Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 60 years old; 2. Patients who are going to take autologous skin grafting surgery in clinic; 3. For patients with total wound area less than 5% (estimated by palm method), the target wound was between 5cm × 5cm and 10cm x 20cm, and the wound location was both lower limbs; 4. Patients who agreed to participate in the study and signed written informed consent.
Exclusion criteria
Exclusion criteria: 1. The patients with diabetes mellitus were judged as poor glycemic control by doctors after regular clinical treatment; 2. Patients with severe malnutrition and albumin 38.5 degree C or WBC > 12x10^9/L; 4. Patients with severe systemic infection who need systemic antibiotics treatment; 5. Patients with tumor, radiotherapy or chemotherapy; 6. Patients complicated with cardiovascular, liver, kidney and blood system and other serious primary diseases and mental diseases; 7. Patients who are known to have allergic history or allergic constitution (allergic to 2 or more allergens) to ingredients or other chemical structures similar to this product and reference substance; 8. Pregnant or lactating women and patients with family planning; 9. Patients who have participated in other clinical studies within one month before enrollment; 10. Patients who are considered unsuitable for clinical study by other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Days of wound healing; | — |
Countries
China
Contacts
Public ContactZhu Shihui
(formerly Department of Burns, Shanghai Changhai Hospital)
Outcome results
None listed