Inflammatory bowel disease
Conditions
Interventions
with anxiety or depression group:Nil
without anxiety or depression group:Nil
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. The patient was diagnosed as inflammatory bowel disease, and the disease was in the active stage; 2. The patients were suitable for hormone therapy; 3. The patient was older than 18 years old.
Exclusion criteria
Exclusion criteria: 1. Patients with active peptic ulcer, recent gastrointestinal anastomosis, severe hypertension, severe diabetes, infection beyond the control of antibiotics, fracture, wound repair period, corneal ulcer; 2. Patients with pituitary tumor, adrenal tumor, adrenocortical hypofunction, adrenal hyperfunction and other diseases affecting HPA axis function; 3. Patients who had or are suffering from severe mental illness and epilepsy; 4. Pregnant women; 5. Patients with poor compliance are difficult to cooperate with follow-up and refuse to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma glucocorticoids;Plasma ACTH;Glucocorticoid receptor subtypes in peripheral blood mononuclear cells;Cytokine; | — |
Countries
China
Contacts
Public ContactZhang Yan
West China Hospital of Sichuan University
Outcome results
None listed