Polycystic ovary syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria of Western medicine and traditional Chinese medicine; 2. Patients aged between 20 and 40 years old; 3. Patients who voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Excluding patients with hyperandrogenemia caused by other reasons, such as Cushing syndrome, delayed congenital adrenal hyperplasia, androgen secreting ovarian and adrenal tumors, and other diseases leading to ovulation dysfunction, such as pituitary or hypothalamic amenorrhea, hyperprolactinemia, premature ovarian failure, etc. 2. Patients with organic diseases or other endocrine diseases were excluded; 3. Patients with severe liver and kidney, cardiovascular and cerebrovascular diseases, hematopoietic system dysfunction and psychosis; 4. Patients who have taken hormone and anticoagulant drugs in the past 3 months or participated in other clinical trials; 5. Patients under 20 years old or over 40 years old; 6. Patients who do not meet the inclusion criteria or incomplete data affect the judgment; 7. Patients who can't adhere to the course of treatment, drop out or lose the follow-up; 8. Patients with severe complications in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TCM symptom score;pregnancy outcome;Coagulation related indicators;Gene transcription level of lncRNA-MALAT1, p38MAPK, TXB2;Expression and phosphorylation of p38 signaling pathway related proteins; | — |
Countries
China
Contacts
Fujian Maternity and Child Health Hospital