Major depressive disorder
Conditions
Interventions
Sponsors
The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital)
Eligibility
Sex/Gender
All
Age
13 Years to 17 Years
Inclusion criteria
Inclusion criteria: Patients group: 1. Provide informed consent; 2. The DSM-IV Axis I disorder was assessed by SCID, which met the diagnostic criteria of DSM-IV depression, and had never received any treatment; 3. HAMD-17 total score >= 17; 4. Aged 13-17 years, at least 6 years of education; 5. Han nationality, right handed; 6. Binocular naked vision or corrected visual acuity was normal. Healthy control group 1. The subjects or their relatives of the third generation of two lineages did not meet any diagnostic criteria of mental illness in DSM-IV, and were not related to the patients group; The other criteria were 2-6.
Exclusion criteria
Exclusion criteria: Patients group: 1. Patients with a history of severe physical or brain organic diseases and craniocerebral trauma; 2. Full scale intelligence quotient (FIQ <= 80) of WAIS-RC; 3. Patients with a history of drug, alcohol or other psychoactive substance abuse; 4. Patients with metal in the body, such as pacemaker; 5. Patients with contraindications to MRI or those who can't tolerate MRI scanning environment, such as claustrophobia. Healthy control group: the same as the patient group. The age, gender and years of education were matched with the patients group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effect;MRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| Safety;Cogntion; | — |
Countries
China
Contacts
Public ContactZheng Wei
The Affiliated Brain Hospital of Guangzhou Medical University (Guangzhou Huiai Hospital)
Outcome results
None listed