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Intensity modulated radiotherapy alone for aged nasopharyngeal carcinoma

Intensity modulated radiotherapy alone for aged nasopharyngeal carcinoma: a phase-II single armed prospective clinical trial

Status
Recruiting
Phases
Phase 2
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037858
Enrollment
Unknown
Registered
2020-09-02
Start date
2020-08-17
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nasopharyngeal carcinoma

Interventions

experimental group :radiotherapy

Sponsors

Fudan University Shanghai Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
70 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients who sign informed consent and are willing to complete the study according to the protocol; 2. Patients older than or equal to 70 years old; 3. Patients with ECoG score of 0-2; 4. Patients with newly diagnosed nasopharyngeal carcinoma confirmed by histology; 5. Patients without distant metastasis; 6. Patients without other malignant tumors; 7. The subjects with normal main organ functions shall meet the following requirements: The blood routine test met the following criteria: (1) HB >= 90g/L (2) ANC >=1.5 x 10^9/L (3) PLT >= 80 x 10^9/L Biochemical examination met the following standards: (1) Bil = 50ml / min (Cockcroft Gault formula).

Exclusion criteria

Exclusion criteria: 1. The patient has any psychological, family, social or geographical conditions that may prevent compliance with the study protocol requirements or follow-up procedures; these conditions should be discussed with the patient before entering the study 2. Patients who are not suitable to be included in the evaluation of relevant physicians; 3. Patients with immunodeficiency and HIV infection; 4. Severe liver and kidney insufficiency; 5. Patients who have received radiotherapy in the head and neck.

Design outcomes

Primary

MeasureTime frame
acute adverse events;

Secondary

MeasureTime frame
3-year Overal survival;

Countries

China

Contacts

Public ContactHongmei Ying

Fudan University Shanghai Cancer Center

yinghm@hotmail.com+86 18317086587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026