Perioperative analgesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients with age >= 65 years old; 2. Patients with hip fracture confirmed by imaging examination; 3. Patients who plan to receive surgery (reduction and fixation or artificial joint replacement) under axial or general anesthesia; 4. Patients who agreed to receive regional nerve block or patient-controlled intravenous analgesia as perioperative analgesia measures; 5. Patients who agreed to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who refused to participate in the study; 2. Patients with BMI > 30kg / m2 or body weight IV grade; 4. Patients with other fractures or multiple injuries; 5. Patients with contraindications for deep nerve block, including but not limited to the following conditions: severe abnormal coagulation function (INR > 1.7, APTT over normal value for 4 seconds, platelet count < 80 x 10^9 / L), trauma or infection at the puncture site, and withdrawal time of new oral anticoagulants (dabigatran, apixaban, rivaroxaban, etc.) was less than 5 days; 6. Patients with chronic opioid dependence and long-term use of various types of analgesics (more than 3 months), such as patients with long-term joint pain; 7. Patients who are unable to communicate due to delirium, dementia, central and / or peripheral nervous system diseases, language disorders or other end-stage diseases; 8. Allergy to local anesthetics and other drugs used in the present study; 9. Other circumstances that the surgeon or investigator deems inappropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| recovery quality at 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| daily NRS pain scores at rest before surgery;NRS pain score at rest 1 hour after intervention;NRS pain score at movement on the set of positon changing when receiving axis anesthesia;NRS pain scores both at rest and with movement at 6, 24, 48, 72 hours after surgery;the rate of complication in hospital;the length of stay in hospital;the recovery qualilty on the day of dischargeday of;the Barthel index on the day of discharge;the modified Harris / Oxford hip score on the day of discharge;the Barthel index 3 months after surgery;the modified Harris /Oxford hip score 3 months after surgery; | — |
Countries
China
Contacts
Peking University First Hospital