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Effect of enteral nutrition intervention on intestinal mucosal repair and immune constitutuion in AIDS patients: a clinical trial

Effect of enteral nutrition intervention on intestinal mucosal repair and immune constitutuion in AIDS patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037839
Enrollment
Unknown
Registered
2020-09-02
Start date
2019-02-11
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

AIDS patients /HIV carriers

Interventions

Control Group:Daily diet or homemade liquid food support program
Experimental Group:Enteral nutrition (Shanghai Licheng nutrition products technology co., LTD.)

Sponsors

The First Affiliated Hospital of Kunming Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with AIDS; 2. Male or female, aged >= 18 years; 3. Patients who can persist in nutrition support treatment for more than 3 months; 4. AIDS patients with nutritional treatment indications; 5. Informed consent of patients / relatives to participate in the study.

Exclusion criteria

Exclusion criteria: 1. The patient was contraindicated to enteral and parenteral nutrition and was known to be allergic to any component of parenteral nutrition for research; 2. Patients with Apache II score > 10; 3. Patients with severe liver, kidney, heart, brain dysfunction, or severe complications such as hypertension, diabetes, coronary heart disease, etc. Patients with severe acute infection, uncontrolled infection, or thickening and chronic infection, and delayed wound healing. Patients with central nervous metastases whose condition was not controlled and had obvious intracranial hypertension or neuropsychiatric symptoms; 4. Patients who participated in other clinical studies; 5. Patients who are known to be in pregnancy or lactation; 6. Patients with poor compliance and unable to cooperate with treatment.

Design outcomes

Primary

MeasureTime frame
lymphocyte subpopulation;viral load;LPS/D - lactic acid/DAO;cytokines;feces 16S DNA sequencing;

Secondary

MeasureTime frame
blood routine examination;blood biochemistry;

Countries

China

Contacts

Public ContactKunhua Wang

The First Affiliated Hospital of Kunming Medical University

kunhuawang1@163.com+86 15271878480

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 8, 2026