Parkinson's disease
Conditions
Interventions
Group 1:Routine anti PD treatment + stretching training
Group 2:Routine anti PD treatment + stretching training + selegiline
Group 3:Routine anti PD treatment + Wuqinxi training
Group 4:Routine anti PD treatment + Wuqinxi training + selegiline
Sponsors
Union Medical College Affiliated Hospital of Tongji Medical College, Huazhong University of science and technology
Eligibility
Sex/Gender
Male
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) According to the 2015 MDS clinical diagnostic criteria, patients with clinically confirmed Parkinson's disease had frozen gait during the course of disease, and the third item of fog-q scale was >= 1 point; 2) The patient or his legal guardian agreed to participate in the trial and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Recently, there is a special person to guide regular exercise, or patients are not beginners of Wuqinxi. 2) Patients with severe organic diseases (malignant tumor, coronary heart disease, uncontrollable hypertension or diabetes, respiratory failure, renal insufficiency requiring dialysis maintenance, etc.), and they are not suitable for the participants due to the doctor's assessment that they may have major health risks in the near future. *Malignant tumor includes patients who have a history of malignant tumor and need to receive radiotherapy and chemotherapy in the past one year or in the future *Coronary heart disease: Patients with recurrent chest discomfort or coronary artery stenosis rate >= 50% confirmed by imaging within 3 years *Uncontrollable hypertension refers to patients who take antihypertensive drugs regularly for one month and whose blood pressure is still higher than 140 / 90mmHg *Uncontrollable diabetes refers to the patients whose fasting blood glucose is higher than 7 mmol / L or postprandial blood glucose is higher than 11.1 mmol / L after 1 month of medication according to the doctor's advice 3) PD patients who have received relevant surgical treatment (including pallidotomy, thalamic lesion, deep brain stimulation or organ transplantation). 4) Patients with severe dementia, namely MMSE score < 10. 5) According to the doctor's evaluation, the patients who are seriously ill and can not complete the follow-up physical exercise or are not suitable for the group.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freezing of Gait Questionnaire;Gait and Falls Questionnaire; | — |
Secondary
| Measure | Time frame |
|---|---|
| UPDRS;Fall events; | — |
Countries
China
Contacts
Public ContactXuebing Cao
Union Medical College Affiliated Hospital of Tongji Medical College, Huazhong University of science and technology
Outcome results
None listed