Clinical significance of Interleukin-6, C-reactive protein and procalcitonin in the early diagnosis of nosocomial infection in preterm infants

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037817

Enrollment

Unknown

Registered

2020-09-02

Start date

2020-09-01

Completion date

Unknown

Last updated

2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nosocomial infection in premature infants

Interventions

Gold Standard:blood culture

Index test:IL-6,CRP and PCT.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) dmore than 3 days after birth; (2) 30 weeks <= gestational age <= 34 weeks; (3) The basic life signs are stable.

Exclusion criteria

Exclusion criteria: (1) Prenatal use of glucocorticoids by mothers; (2) Community-acquired infections; (3) Incomplete clinical data records; (4) Antibiotics should be applied before the first blood collection; (5) Children with suspected genetic metabolic diseases, congenital malformations, asphyxia before or during labor or immunodeficiency.

Design outcomes

Primary

Measure	Time frame
Interleukin-6;C-reactive protein;procalcitonin;SEN, SPE, ACC, AUC of ROC, PPV, NPV;	—

Countries

China

Contacts

Public ContactJianhua Fu

Shengjing Hospitai of China Medical University

liying58522@163.com+86 18940251830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026