Transnasal humidifified rapid insufflflation ventilatory exchange for oxygenation of children during airway foreign body removal: a prospective randomised controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037810

Enrollment

Unknown

Registered

2020-09-02

Start date

2020-09-20

Completion date

Unknown

Last updated

2021-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric airway foreign body aspiration

Interventions

THRIVE+ManuJet:THRIVE combined with manual jet ventilation

ManuJet:manual jet ventilation

Eligibility

Sex/Gender

All

Age

1 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. Aged 12 months-6 years; 2. ASA I~II; 3. History of foreign body aspiration; 4. Preoperaitve oximetry at or above 97% without oxygen supplement; 5. Plan for rigid bronchoscopic foreign body removal.

Exclusion criteria

Exclusion criteria: 1. Upper airway obstruction; 2. Known or predicted difficult tracheal intubation; 3. Known or predicted difficult mask ventilation; 4. Congenital heart or lung diseases; 5. BMI over 30; 6. Contraindication for neuromuscular blockade; 7. Risk of reflux and aspiration; 8. Allergy to any drug used in anesthesia or surgery.

Design outcomes

Primary

Measure	Time frame
apnoeic time;number of manual jet ventilation circles;	—

Secondary

Measure	Time frame
hypoxemia during emergence;emergence quality;laryngeal mask removal time;duration of emergence;duration of surgery;	—

Countries

China

Contacts

Public ContactLi Wenxian

Eye & ENT Hospital, Fudan University

liwenxian@eentanesthesia.com+86 13917426838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026