Depth of anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Select patients who have undergone elective unilateral knee replacement surgery at Shanghai Sixth People’s Hospital from September 2020 to November 2020 by the same group of surgeons, ASA grade I-III, NYHA grade I-III, age 18 -75 years old, BMI18-25Kg/m^2, regardless of gender.
Exclusion criteria
Exclusion criteria: 1. Patients with a history of central nervous system or cerebrovascular disease; 2. Patients with a history of abuse of alcohol or opioids or other psychotropic drugs; 3. Patients who are at risk of difficult airway or for any other reason and cannot accept conventional intravenous anesthesia induction; 4. Patients with severe heart, brain, liver, lung, and kidney insufficiency; 5. Patients with body mass index BMI25 Kg/m^2; 6. Patients who cannot provide informed consent or cannot be followed up for 24 hours after surgery 7. Patients with peripheral neuropathy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total usage and adjustment times of propofol;Remifentanil total usage and adjustment times; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of adverse events during surgery;Wake up quality; | — |
Countries
China
Contacts
Shanghai Sixth People's Hospital