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Effects of different SVV thresholds based goal-directed fluid therapy on tourniquet related hemodynamic fluctuations

Effects of different SVV thresholds based goal-directed fluid therapy on tourniquet related hemodynamic fluctuations

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037737
Enrollment
Unknown
Registered
2020-08-31
Start date
2020-09-01
Completion date
Unknown
Last updated
2022-01-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee replacement

Interventions

Sponsors

The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 65 Years

Inclusion criteria

Inclusion criteria: One hundred and Sixty ASA physical status I or II patients of both sexes, aged 40 to 65 years, Preoperative normal pulmonary function,and no received radiotherapy, chemotherapy and immunosuppressive agents, scheduled for elective thoracoscopic lobectomy under OLV. The same type of surgery is operated by the same group of doctors, and written informed consent was obtained from all enrolled patients.

Exclusion criteria

Exclusion criteria: 1. severe liver and kidney dysfunction, coagulation abnormalities and perioperative allogeneic blood; 2. autoimmune disease or immunocompromised patients; 3. cardiovascular adverse reactionsgastrointestinal bleeding in patients after using NSAIDs; 4. high blood pressure, severe heart failure; 5. enoxacin, lomefloxacin, norfloxacin being used; 6. others is unsuitable for selected.

Design outcomes

Primary

MeasureTime frame
The SUV of hypotension;

Secondary

MeasureTime frame
The change value of Lactic;The change value of CO;The change value of SV;The change value of Inferior vena cava collapse index;

Countries

China

Contacts

Public ContactShu Shuhua

The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China

sshhf@189.cn+86 15375472196

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026