The research of multi-modality precise diagnosis, prognosis forecasting and TMS analeptic treatment in patients with brain injury-induced disorders of consciousness

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037731

Enrollment

Unknown

Registered

2020-08-30

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain injury-induced disorders of consciousness

Interventions

experiment group1:Transcranial Magnetic Stimulation

control group1:pseudo-TMS

control group1:regular treatment

experiment group1:TMS

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients suffering from brain injury aging between 18 to 65; 2. Patients with disorders of consciousness conforming the diagnostic criteria of coma, vegetative state and minimal conscious state; 3. Patients conditions allows fMRI as well as the fMRI indicates the relatively integral connectivity between PCC-TPJ; 4. With the literal permission of patientsfamily members.

Exclusion criteria

Exclusion criteria: 1. Patients with apparent serious diseases including psychological diseases or cardiac, pulmonary, hepatic or renal malfunction. 2. Patient receiving some treatments which can disturb fMRI assessment. 3. Patients with unstable vital signs or dependent on ventilation machine to support ones lives. 4. Patients with such plentiful sputum that entailing aspiration of sputum effecting the fMRI assessment.

Design outcomes

Primary

Measure	Time frame
high density EEG;functional MRI;	—

Countries

China

Contacts

Public ContactWu Xuehai

Huashan Hospital Affiliated to Fudan University

wuxuehai2013@163.com+86 13764880571

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026