gastroparesis
Conditions
Interventions
1:Conservative treatment group
2:6 o'clock longitudinal myotomy
3:Longitudinal myotomy at 6 o'clock and 4 o'clock
Sponsors
Shanghai General Hospital, Shanghai Jiao Tong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients must meet all of the following inclusion criteria to be eligible for inclusion in the study: 1. Aged between 18-85; 2. Informed consent of the patient's family to participate in the study (2. Informed consent of the patient's family to participate in the study) and consent to participate in the study. 3. According to the clinical practice of American Gastroenterology Association in 2021, gastroparesis Management: gastroparesis is defined as: (1) Symptoms associated with severe gastric emptying disorders may include nausea, vomiting, abdominal pain, gastric fullness, early satiety, loss of appetite, nausea, postprandial fullness and / or abdominal distention. Severe gastric emptying disorder was defined as the course of disease greater than 6 months and the failure of drug treatment; The main symptom index (gcsi) score of gastroparesis was > 1.5; (2) Solid gastric emptying scintigraphy confirmed that the 3H gastric retention rate was more than 30%, or the 4H gastric retention rate was more than 10%, or the gastric emptying time delay exceeded the normal value by 50%; Or liquid gastric emptying scintigraphy was delayed for more than 80 minutes. (3) Recent (< 3 months) or preoperative gastroscopy showed no signs of ulcerative lesions or gastric outlet obstruction.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria will not be included in the study: 1. Those who cannot tolerate endoscopy; 2. Patients with endoscopy or anesthesia contraindications; 3. Coagulation dysfunction; 4. Abdominal pain caused by functional gastrointestinal disease; 5. Under 18 years old or over 85 years old; 6. Join other clinical trials 3 months before onset; 7. Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| GCSI;gastric emptying scintigraphy; | — |
Countries
China
Contacts
Public ContactBaiwen Li
Shanghai General Hospital, Shanghai Jiao Tong University
Outcome results
None listed