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Study on the effect of drug intervention on perioperative complications of general anesthesia

Study on the effect of drug intervention on perioperative complications of general anesthesia

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037686
Enrollment
Unknown
Registered
2020-08-30
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-11-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Perioperative complications of general anesthesia

Interventions

experimental group :Drug intervention
control group:Equivalent saline

Sponsors

General Hospital of Tianjin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients undergoing tracheal intubation under general anesthesia for elective surgery from September 1, 2020 to July 31, 2022 in Tianjin Medical University General Hospital.

Exclusion criteria

Exclusion criteria: 1. The object of smoking; 2. Subjects with body mass index (BMI) over 28 kg / m2; 3. Patients with elevated intracranial pressure, intra-abdominal pressure or intraocular pressure before operation; 4. Patients with a history of respiratory diseases, such as asthma, chronic cough and upper respiratory tract infection within two weeks; 5. Patients with history of other systemic diseases, including gastroesophageal reflux, hypertension, diabetes, heart disease, liver and kidney dysfunction, and adrenocortical insufficiency; 6. Patients with a long history of taking opioids or other cough causing drugs, such as angiotensin-converting enzyme inhibitors, and antitussive drugs such as bronchodilators and steroids.

Design outcomes

Primary

MeasureTime frame
Perioperative cardiovascular complications of general anesthesia;Cough;Amyostasia;Cognitive impairment;Respiratory inhibition;

Countries

China

Contacts

Public ContactDong Beibei

Department of Anesthesiology, General Hospital of Tianjin Medical University

senyu1219@163.com+86 13682081217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026