ground glass opacity
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) In patients with early ground-glass pulmonary nodules, the size of the nodules <= 19mm; (2) Elderly aged 70 or above; (3) The main organs function well and the blood clotting function is normal; (4) Before the subjects were enrolled, they signed informed consent to participate in the study and abide by the study procedures.
Exclusion criteria
Exclusion criteria: Patients with previous cancers, pneumonectomy for other reasons, patients with atelectasis, pleural effusion, multiple adenocarcinoma, preoperative radiotherapy and chemotherapy, etc. Specific standard is as follows: (1) can't control the systemic hemorrhagic diseases, serious high blood coagulation state, blood coagulation function disorder or subjects are using drugs affect the function of blood coagulation; (2) serious complications, such as heart function class III and IV (NYHA standard New York heart association), the occurrence of myocardial infarction within six months or more than 3 (including 3) angina pectoris, brain trauma, brain parasitic diseases, apoplexy, hepatic encephalopathy, autoimmune hepatitis, cirrhosis of the liver decompensation period patients with hepatic insufficiency, renal insufficiency; (3) Previous history of other malignant tumors, except cured basal cell carcinoma or squamous cell carcinoma of the skin and carcinoma in situ of the cervix; (4) The accompanying diseases (including but not limited to hypertension, severe diabetes, active infection, thyroid disease, etc.) that, according to the judgment of the researcher, seriously endanger the safety of the patient or affect the completion of the study; (5) Any mental or cognitive impairment, emotional instability, which may limit their understanding of informed consent, implementation, and compliance with the study; (6) Other conditions in which the researcher considers him/her unfit to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1 year disease-free survival time;2 years disease-free survival time;quality of life;Major complications following RFA or surgical excision; | — |
Countries
China
Contacts
Huadong Hospital affiliated to Fudan University