hepatitis Cirrhosis
Conditions
Interventions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 20 and 70 years old (inclusive); 2. It meets the diagnostic criteria of hepatitis B cirrhosis; 3. Liver and gallbladder damp-heat syndrome group: meeting the criteria of disease diagnosis and liver and gallbladder damp-heat syndrome; 4. Liver and kidney yin deficiency syndrome group: meeting the standards of disease and liver and kidney yin deficiency syndrome; 5. Hidden syndrome group: meeting the criteria of disease and hidden syndrome; 6. Normal control group: Healthy volunteers matched with the gender and age of the case group were selected; 7. The person or his guardian agrees to participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Complicated with conjunctivitis, conjunctival hemorrhage, ocular trauma, surgical eye and other ophthalmic diseases; 2. There are overlapping infections of hepatitis A, C, D and E, fatty liver, or other severe hepatitis; 3. Patients with heart, lung, brain, endocrine, hematopoiesis, nerve and other systemic diseases and allergic to drugs; 4. Patients with malignant tumor and connective tissue disease; Clearly have other important diseases; 5. Pregnant or lactating women and allergic people; 6. Those who have mental disorders can't cooperate; 7. Those who participate in other clinical trials or other situations that researchers think are not suitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eye image (eye surface and fundus); | — |
Secondary
| Measure | Time frame |
|---|---|
| Magnetic resonance /CT/ elastography /B-ultrasound (liver, gallbladder, pancreas, spleen and kidney), etc;Biochemical examination: liver and kidney function/routine blood test/coagulation/blood lipid;TCM syndrome scale integral (including PRO scale and physical sign scale), tongue picture and pulse picture; | — |
Countries
China
Contacts
Public ContactZhang Hua
Institute of Liver Diseases, Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed