Polycystic Ovary Syndrome
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with polycystic ovary syndrome and overweight or obese 1. polycystic ovary syndrome 1) patients who meet the Chinese diagnostic criteria of PCOS (2018); 2) patients who had not previously treated PCOS with metformin; 3) patients who had not previously treated other diseases such as diabetes with metformin; 2. overweight and obese patients 1)The standard weight of a patient 1) evaluated on the basis of BMI (Body Mass Index), BMI is the number of kilograms divided by the square of the number of meters in height, which is a commonly used international measure of weight and health. 2) BMI >= 24 is considered overweight and BMI >= 28 is considered obese according to the Chinese reference standard;
Exclusion criteria
Exclusion criteria: Patients with 1) Other serious diseases include coronary heart disease (angina pectoris, myocardial infarction, coronary artery regeneration process or abnormal ECG Q (ECG)), stroke (ischemic or hemorrhagic, including transient ischemic attack), etc.; 2) patients with severe gastrointestinal diseases with nutritional disorders or which may affect the effects of nutritional interventions; 3) any other medical condition that the maximum duration of survival is less than 5 years; 4) patients with addictive sexual tendencies such as substance abuse or chronic alcohol or alcohol dependence; 5) patients who have significant implementation difficulties in changing their eating habits or following doctor's orders to improve their living habits or who are unable to follow up; 6) allergy to metformin or severe side effects of previous use of metformin are intolerable.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Menstrual Recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Natural Pregnancy;Glucose Tolerance;Insulin Resistance;Blood Lipid;Sexual Hormones;Blood Pressure;Body Mass Indix;Blood Routine Examination;Blood Serum Iron;Ferritin;Gene;Growth and development of offspring;Intestinal flora; | — |
Countries
China
Contacts
Beijing Chaoyang Hospital, Capital Medical University