Cardiopulmonary bypass cardiac surgery
Conditions
Interventions
Gold Standard:The Delirium assessment scales (ICU-CAM and CAM scales) were used to diagnose postoperative delirium.
Montreal Scale (MoCA) was used to diagnose delayed neurocognitive recovery.
technology 
(LC-MS) 
was 
used 
to 
Sponsors
Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Type of surgery: extracorporeal circulation cardiac surgery (coronary artery bypass grafting or valve replacement); 2) Ages 18-75 years, regardless of gender; 3) No history of alcohol addiction, or no history of alcohol use in the last two weeks; 4) the New York heart association (NYHA) heart function class II or III, left ventricular ejection fraction (EF) > 50%; 5) Preoperative white blood cell count was normal; 6) Admitted to ICU after surgery; 7) plan to be hospitalized for > for 24 hours after surgery.
Exclusion criteria
Exclusion criteria: 1) Refuse to participate; 2) Previous history of heart surgery or secondary heart surgery; Acute cardiac tamponade and myocardial infarction, severe sinus bradycardia, atrioventricular block or pathological sinoatrial node syndrome; 3) Previous chronic pulmonary disease, pulse oxygen saturation = 8 points; 10) Inability to communicate due to illiteracy, language impairment or major hearing or visual impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| metabolomics studies; | — |
Secondary
| Measure | Time frame |
|---|---|
| biochemical indicators;cardiopulmonary bypass time;postoperative delirium;Delayed Neurocognitive recovery;hospital stays;Side effects; | — |
Countries
China
Contacts
Public ContactYu Chen
Jiangsu Province Hospital
Outcome results
None listed