Type 2 disease
Conditions
Interventions
Case series:Insulin degludec/aspart
Sponsors
Peking Union Medical College Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients with type 2 diabetes >= 18 years old; (2) Diagnosis of type 2 diabetes over 6 months; (3) Premix insulin 3 times a day or basal meal insulin with or without oral hypoglycemic agents (OADs) for at least 12 weeks; (4) BMI <= 35kg/m2.
Exclusion criteria
Exclusion criteria: (1) Insulin allergy; (2) Total daily dose of insulin > 100U/d; (3) Use of drugs that may interfere with glucose metabolism before the experiment; (4) Women who are pregnant, breastfeeding or planning to pregnancy; (5) Acute and chronic infection and tumor; (6) History of cardiovascular and cerebrovascular diseases within 3 months, including stroke, decompensated heart failure (NYHA III or IV), myocardial infarction, coronary artery bypass grafting or angioplasty; (7) Untreated or uncontrolled severe hypertension, in which severe hypertension refers to SBP>=180mmHg and/or DBP>=100mmHg; (8) Severe liver or kidney function damage; (9) Recurrent episodes of severe hypoglycemia or hypoglycemia coma or hospitalization due to diabetic ketoacidosis within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c; | — |
Secondary
| Measure | Time frame |
|---|---|
| FBG;SMPG;Total daily dose of insulin needed;DTSQ;the incidence of hypoglycemia; | — |
Countries
China
Contacts
Public ContactHuabing Zhang
Department of Endocrinology, Key Laboratory of Endocrinology, National Health Commission, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences
Outcome results
None listed