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Single-center clinical study of early diagnosis of diabetic cardiomyopathy with FLIM

Single-center clinical study of early diagnosis of diabetic cardiomyopathy with fluorescence lifetime imaging microscopy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000037566
Enrollment
Unknown
Registered
2020-08-28
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic cardiomyopathy

Interventions

Case series:no

Sponsors

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. male or female, aged 18-80 years old; 2. echocardiography showed that the cardiac structure was normal and the left ventricular ejection fraction was more than 50%; 3. patients with type 2 diabetic mellitus; 4. body mass index (BMI) 20-25kg/m2 in male and 19-24kg/m2 in female; 5. no other drugs excepte hypoglycemic drugs were taken in one month; 6. sign informed consent form before entering this study.

Exclusion criteria

Exclusion criteria: 1. patients with type 1 diabetes mellitus; 2. patients with diabetic ketoacidosis in the past; 3. patients with coronary heart disease or with myocardial ischemia indicated by ECG; 4. EGFR < 60 ml/min/1.73m2 in recent one month; 5. Chronic liver disease, or the levels of alanine aminotransferase and glutamic oxaloacetic transaminase were more than 3 times of the upper limit of the normal before enrollment; 6. Abnormal thyroid function; 7. Abnormal tumor index; 8. Dyslipidemia; 9. Pregnant and lactating women; 10. Allergy to contrast media.

Design outcomes

Primary

MeasureTime frame
fluorescence lifetime;

Countries

China

Contacts

Public ContactGuo Kai

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine

guokai@xinhuamed.com.cn+86 13636511066

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026