Tuberculosis
Conditions
Interventions
Gold Standard:MTB conventional culture from sputum
Index test:Multi-gene 
 
and 
acid-fast 
Sponsors
Huadong Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: From Jan 2020 to Dec 2021, patients with TB or suspected TB from Huadong Hospital and Pulmonary Hospital, as well as patients infected with NTM, are of any age or gender. The diagnosis of pulmonary tuberculosis adopts the diagnostic criteria and treatment principles in the WS288-2017 and the fourth edition of the WHO TB treatment guidelines. Cough, spit >=2w, or hemoptysis is a suspicious symptom of pulmonary TB. Imaging examinations must have typical imaging findings. The pathogenic diagnosis must be based on the detection of related pathogens or specific nucleic acids from sputum samples. MTB was cultivated in the sample. The diagnostic criteria for extrapulmonary TB is positive MTB culture; pathological biopsy confirmed positive for caseous granuloma or acid-fast bacilli; chest X-ray showed miliary shadows of both lungs; anti-TB treatment is effective. NTM infection criteria: clinically exclude TB, or detect NTM in clinical samples.
Exclusion criteria
Exclusion criteria: The patient had no clinical symptoms of tuberculosis and no signs of tuberculosis in imaging. The laboratory test results showed that no colonies were found after the sample was cultured for 8 weeks. There were no mycobacteria in the 3 sputum smear microscopy. The T-spot experiment and GeneXpert-MTB-RIF also showed Negative.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MTB; | — |
Countries
China
Contacts
Public ContactHu Zhao
Huadong Hospital
Outcome results
None listed