gynecologic disease
Conditions
Interventions
one:Preoperative intravenous Remimazolam
two:Preoperative oral Estazolam
three:Preoperative oral Estazolam and intravenous Remimazolam
four:Preoperative intravenous normal saline
Sponsors
Lianyungang First People's Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Those who voluntarily participate in this research and sign relevant informed consent; 2) Female patients aged 18-65 years, body mass index (BMI) 18-30kg/m2, complete clinical data; 3) Those who are classified by the American Association of Anesthesiologists (ASA) I / II; 4) Those who receive surgical treatment on schedule and are tolerant to the relevant drugs in this study; 5) Diagnose patients with non-malignant tumors.
Exclusion criteria
Exclusion criteria: 1) Patients with a history of oral sedative analgesics (benzodiazepines, barbiturates, non-steroidal anti-inflammatory drugs, opioid analgesics, etc.) within 14 days before surgery; 2) Patients with cardiopulmonary dysfunction; 3) Those with a history of mental illness, alcohol abuse, drug abuse, and chronic pain; 4) Those with severe liver and kidney dysfunction; 5) Patients with contraindications or allergic reactions to the use of benzodiazepines; 6) Patients who cannot understand the meaning of the scoring scale and cannot master the use of self-control analgesia pump; 7) Preoperative anxiety score (VAS-A) > 0.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pain score;anxious score;Dosage of analgesics; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality;Operation duration;Intraoperative medication;Incidence of postoperative adverse reactions;patient satisfaction;Length of stay (LOS) in the hospital;Extubation time;Pain related factor; | — |
Countries
China
Contacts
Public ContactZhi-Bin Zhao
Lianyungang First People's Hospital
Outcome results
None listed