Investigation of GABA levels, changes in microstructure and function and relation with cognitive impairment in patients with NMOSD: a multimodal MRI study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000037477

Enrollment

Unknown

Registered

2020-08-28

Start date

2020-10-20

Completion date

Unknown

Last updated

2020-10-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NMOSD

Interventions

NMO:Nil

HC:Nil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. right-handed; 2. meet the criteria for diagnosis of NMOSD; 3. have no history of relapse within the preceding 2 weeks.

Exclusion criteria

Exclusion criteria: 1. Severe visual or hearing impairment; 2. a history of brain tumor or head trauma or cerebrovascular disease; 3. a history of neurological or psychiatric disorder; 4. previous or current substance or alcohol abuse.

Design outcomes

Primary

Measure	Time frame
GABA;Gray matter volume/White matter volume;Functional brain connectivity;	—

Countries

China

Contacts

Public ContactLI Yonggang

Department of Radiology, the First Affiliated Hospital of Soochow University

liyonggang224@163.com+86 13776006850

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026