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Study on therapeutic effect of hyperthermic intraperitoneal chemotherapy (HIPEC) on patients of pancreatic cancer

Study on therapeutic effect of hyperthermic intraperitoneal chemotherapy (HIPEC) on resectable pancreatic cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037433
Enrollment
Unknown
Registered
2020-08-28
Start date
2020-09-01
Completion date
Unknown
Last updated
2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pancreatic cancer

Interventions

2:Operation+HIPEC

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Men and women aged 18 to 75 with confirmed pancreatic cancer; (2) No lymph node involvement or lymph node involvement can be resected; (3) No distant metastasis except peritoneum (M0);(4) EGCO score 1,500 / mm3, platelet >150,000/ L, creatinine clearance > 60 mL/min according to Cockcroft formula); (6) No CRS+HIPEC treatment was performed before entering the experiment; (7) Informed consent of the patient and his/her family.

Exclusion criteria

Exclusion criteria: 1. Extraperitoneal metastasis (M1); 2. Pancreatococcygeal combined splenectomy; 3. High degree of tumor differentiation and histological characteristics of signet-ring cells; 4. The tumor or metastatic lymph nodes cannot be resected; 5. Coexisting with another malignant tumor disease; 6. Severe liver, kidney and cardiovascular dysfunction; 7. Unable to tolerate HIPEC treatment; 8. Chemotherapy was performed before the experiment; 9. Pregnant or lactating women.

Design outcomes

Primary

MeasureTime frame
Time to relapse;Distant metastasis;Disease-free survival;Overall survival;Survival rates;

Countries

China

Contacts

Public ContactHeshui Wu

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

heshuiwu@hust.edu.cn+86 13260580108

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026