MCI
Conditions
Sponsors
Longhua Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 40-85 years old; 2. chief complaint of memory impairment and memory difficulty confirmed by others; 3. Mini Mental State Examination (MMSE) score of 24-30 points; 4. Hamilton Depression Rating Scale score <=12 points (17 items); 5. no obvious cerebrovascular disease: Hachinski ischemic score (his) score <=4; 6. CT or MRI within 12 months before screening There was no evidence of infection, infarction or other focal injury, and no suggestive clinical symptoms related to neurological diseases; lacunar infarction in a non critical brain area could be allowed and not be considered to affect the cognitive impairment of the subjects; 7. sufficient visual and auditory resolution was required for neuropsychological tests; 8. TCM Syndrome Differentiation for kidney essence deficiency, Qi and blood deficiency patients.
Exclusion criteria
Exclusion criteria: 1. Positive dementia: MMSE <=24 points or meeting the DSM - IV dementia diagnostic criteria; 2. obvious cerebrovascular diseases: his greater than 4 points or clinical cerebral infarction; 3. moderate depression or another mental disease in line with DSM - IV standard in the past two years; 4. the past 2 years He had a history of alcohol or drug abuse or addiction (DSM - IV standard) within one year; 5. history of schizophrenia (DSM - IV standard); 6. any obvious neurological diseases such as Parkinson's disease, Huntington's disease, normal intracranial pressure hydrocephalus, brain tumor, progressive supranuclear palsy, epilepsy, subdural edema, multiple sclerosis, severe head trauma, with persistent neurological deficits or known structural brain abnormalities; 7. can not follow the research procedure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE;MoCA; | — |
Countries
China
Contacts
Public ContactGu Chao
Shanghai Longhua University Hospital of traditional Chinese Medicine
Outcome results
None listed