Parkinson 's disease
Conditions
Interventions
intervention group:innovative “Wuqinxi” exercise therapy in combination with routine anti PD medication treatment
Sponsors
Xinhua Hospital, Affiliated to Shanghai JiaoTong University, School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) patients who has been clinically diagnosed with PD according to the 2015 international MDS PD criteria. (2) patients at H-Y grade of 1 and 2 level. (3) patients that have been treated with stable anti Parkinson medications and could walk independently. (4) patients or their legal guardians have agreed to participated in the clinical study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: (1) patients that have exercise habits or have engaged in Wuqinxi exercise before the study recruitment; (2) patients whom the researchers considered not suitable for this study; (3) patients who were diagnosed with atypical parkinsonism or secondary parkinsonism or hereditary Parkinson disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time point of motor complication (wearing-off phenominon) occurrence during the study;the difference value between the MDS-UPDRS-III score at baseline and MDS-UPDRS-III score after intervention; | — |
Secondary
| Measure | Time frame |
|---|---|
| the difference value between PD-NMSQ30 score at baseline and the PD-NMSQ30 score after intervention;the difference value between the gait parameters at baseline and the gati parameters after the intervention.;the change between the activated brain areas and network at baseline and after the intervention;the difference value between the PDQ-8 score at baseline and the PDQ-8 score after intervention;the difference value between CGI score at baseline and CGI score after intervention; | — |
Countries
China
Contacts
Public ContactZhenguo Liu
Xinhua Hospital, Affiliated to Shanghai Jiao Tong University, School of Medicine
Outcome results
None listed