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Efficacy evaluation and safety analysis of TACE combined with HIFU in the treatment of liver metastases unresectable colorectal cancer

Efficacy evaluation and safety analysis of TACE combined with HIFU in the treatment of liver metastases unresectable colorectal cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037382
Enrollment
Unknown
Registered
2020-08-28
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-10-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

experimental group:TACE+HIFU
control group: TACE

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Patients with liver metastases from colorectal have pathological confirmation, CT clear liver metastases, and enhanced CT scans strongly suggest a rich blood supply (advanced arterial tumors have obvious enhancement). 2. Liver metastases <= 5, no obvious signs of liver failure, excluded lung, brain and other distant metastases, no intestinal obstruction, rejection of surgical treatment or no surgical treatment, no portal vein thrombus. 3. Diagnostic criteria: 1) Imaging diagnosis: CT and MRI confirmed liver metastases; pathologically clear colorectal; laboratory tests: CEA, CA199, CA242, CA-125, CA242, CA50. 4. The patient is 40-85 years old and participates voluntarily; the patient and his family agree and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. There are obvious signs of liver failure, Child-Pug C grade of liver function; 2. Contraindications for TACE surgery such as portal vein thrombus; 3. There are obvious distant metastases, such as lung and brain, and intestinal obstruction; 4. Cases with poor compliance with the test; the course of treatment has not ended, and the patient withdraws due to other reasons.

Design outcomes

Primary

MeasureTime frame
ORR;

Countries

Shanghai

Contacts

Public ContactLi Liubo

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

771329280@qq.com+86 13795375689

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026