Amyotrophic lateral sclerosis
Conditions
Interventions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All voluntarily registered patients with lateral sclerosis of muscular dystrophy. (1) There must be: A: evidence of clinical, electrophysiological or neuropathic degeneration of inferior motor neurons; B: Clinical examination confirmed the degeneration of upper motor neurons; C: Symptoms that develop gradually in one area or from one area to another are detected by history or examination. (2) At the same time: A: signs of degeneration of lower motor neurons and/or upper motor neurons that can be explained by electrophysiological or pathological evidence of other diseases; B: Neuroimaging evidence of other diseases can explain the clinical and electrophysiological characteristics. 2) Clinical diagnostic study of ALS: Medical history, physical examination and neurological examination should detect clinical evidence of upper and lower motor neuron injury in four areas of the central nervous system (brain stem, neck, chest and lumbosacral medulla), and perform neuroelectrophysiological, neuroimaging and clinical laboratory tests according to clinical indications, excluding other diseases.
Exclusion criteria
Exclusion criteria: Patients who do not meet the diagnosis of sclerosis on the side of muscular atrophy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amyotrophic lateral sclerosis scale for patients with amyotrophic lateral sclerosis before and after treatment;Amyotrophic lateral sclerosis scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tracheotomy time;Time of death; | — |
Countries
China
Contacts
Public ContactXuying Zhu
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Outcome results
None listed