Atrial Fibrillation
Conditions
Interventions
PRIMA stepwise group:PRIMA stepwise protocol for catheter ablation
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 30 to 80 years old; 2. AF lasting >= 1 month; and atrial fibrillation was detected preoperatively. 3. Agree and sign informed consent; 4. Patients must be willing and able to comply with all peri-ablation and follow-up requirements.
Exclusion criteria
Exclusion criteria: 1. Patients with untreated hyperthyriodism or hypothyriodism(except for thyroid hormone replacement therapy); 2. Previous surgery due to atrial fibrillation, whether cardiac surgery or percutaneous interventional procedure (including surgical maze operation, catheter ablation and left atrial appendage occlusion procedure, etc.); 3. Severe organic heart disease (such as severe mitral stenosis or reflux, severe aortic valve stenosis or reflux, hypertrophic obstructive cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, etc.); 4. Contra-indication to heparin or oral anticoagulant therapy; 6.Patients with severe pulmonary disease(such as restricted pulmonary disease, severe collapsed lung, etc); 6. Existence of thrombus, tumor or other conditions inference catheter operation in the atrium; 7. The anteroposterior diameter of left atrium >55mm (2D echocardiography, long axis view beside sternum); 8. Pregnant women.; 9. Patients with active heart or systemic infections; 10. Allergic to iodine; 11. Patients with severe liver or kidney disease;(ALT or billirubin >3ULN,Creatinine clearance <30ml/min); 12. Novel Coronavirus infected patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom from documented AF/AT episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications, 3 months after ablation is a blank period; | — |
Secondary
| Measure | Time frame |
|---|---|
| Freedom from documented AF episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications;Freedom from documented AT episodes > 30 seconds at 12 months after one ablation procedure without antiarrhythmic medications;Procedure time;Fluoroscopy time;Ablation time;Relationship of acute AF termination to long-term procedural outcome.; | — |
Countries
China
Contacts
Public ContactSongwen Chen
Shanghai General Hospital
Outcome results
None listed