Congenital diaphragmatic hernia
Conditions
Interventions
intervention group:sildenafil + conventional therapy
control group:conventional therapy
Sponsors
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 5 Years
Inclusion criteria
Inclusion criteria: 1. Children with congenital diaphragmatic hernia diagnosed before childbirth; 2. Children born in our hospital and treated with multidisciplinary diagnosis and treatment mode; 3. The children met the criteria of pulmonary hypertension by echocardiography; 4. After informing the parents of all aspects of the clinical treatment study, the parents voluntarily confirmed their consent to participate in the clinical treatment study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiac malformations; 2. Patients with chromosomal abnormalities; 3. Patients whose family members give up treatment and withdraw during the treatment process; 4. Patients who did not follow the diagnosis and treatment path during the treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pulmonary arterial pressure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;PaO2; | — |
Countries
China
Contacts
Public ContactPan Weihua
Xinhua Hospital Affiliated to Medical College of Shanghai Jiaotong University
Outcome results
None listed