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Effect of Nian-Mo granules for IgA nephropathy by regulating intestinal microecology

Effect of Nian-Mo granules for IgA nephropathy by regulating intestinal microecology

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000037300
Enrollment
Unknown
Registered
2020-08-27
Start date
2020-10-01
Completion date
Unknown
Last updated
2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA Nephropathy

Interventions

Sponsors

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. IgA nephropathy was confirmed by renal biopsy; 2. The glomerular filtration rate (eGFR) was more than 50 ml / min·1.73 m2; 3. Aged >= 18 years and <= 80 years, regardless of gender; 4. They agreed to participate in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Secondary IgAN, such as cirrhosis, lupus nephritis, hepatitis B associated nephritis, purpura nephritis, etc.; 2. Those who use steroid or immunosuppressant within 3 months; 3. No abnormality was found in stool microscopic examination, and no antibiotics or lactulose drugs affecting fecal pH value were used within 3 months before collecting fecal and blood samples; 4. Severe damage of heart, brain and liver function or other serious basic diseases.

Design outcomes

Primary

MeasureTime frame
Urine protein quantification;Microalbuminuria;renal function (Serum creatinine);

Secondary

MeasureTime frame
routine urine test;Urinary N-acetyl-ß-D-glucosidase;Blood lipids (cholesterol, triglycerides, low density lipoprotein);Serum albumin;

Countries

China

Contacts

Public ContactHan Shi-sheng

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

hanss8612@163.com+86 13774380819

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026