IgA Nephropathy
Conditions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. IgA nephropathy was confirmed by renal biopsy; 2. The glomerular filtration rate (eGFR) was more than 50 ml / min·1.73 m2; 3. Aged >= 18 years and <= 80 years, regardless of gender; 4. They agreed to participate in the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Secondary IgAN, such as cirrhosis, lupus nephritis, hepatitis B associated nephritis, purpura nephritis, etc.; 2. Those who use steroid or immunosuppressant within 3 months; 3. No abnormality was found in stool microscopic examination, and no antibiotics or lactulose drugs affecting fecal pH value were used within 3 months before collecting fecal and blood samples; 4. Severe damage of heart, brain and liver function or other serious basic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urine protein quantification;Microalbuminuria;renal function (Serum creatinine); | — |
Secondary
| Measure | Time frame |
|---|---|
| routine urine test;Urinary N-acetyl-ß-D-glucosidase;Blood lipids (cholesterol, triglycerides, low density lipoprotein);Serum albumin; | — |
Countries
China
Contacts
Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine