hypertension
Conditions
Sponsors
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Patients with essential hypertension who have taken antihypertensive drugs or meet the diagnostic criteria of Hypertension in Chinese Guideline for Prevention and Treatment of Hypertension 2010: under the condition of not using antihypertensive drugs, blood pressure of patients with systolic blood pressure >= 140mmHg and/or diastolic blood pressure >= 90mmHg shall be measured three times on the same day; 2. The questionnaire on the mental health status of patients was conducted by professional psychological consultants, including GAD7 anxiety Screening Scale and Hamilton anxiety Scale (HAMA), GAD7>= 5 and = 7 and = 7 and <= 24 points. 3. Conform to the syndrome differentiation standard of Yin deficiency and Yang hyperactivity in TCM; 4. Age in 60~90 years old, gender is not limited; 5. Stop taking other similar Traditional Chinese medicines and proprietary Chinese medicines during clinical observation; 6. Cooperate with the questionnaire and the investigator, informed consent.
Exclusion criteria
Exclusion criteria: 1. Acute myocardial infarction, unstable angina pectoris; 2. Patients with other cardiac diseases or severe cardiac insufficiency (NYHA cardiac function grade > level III); 3. Patients with poor control after standardized treatment of hypertension (blood pressure > 170/105mmhg); 4. severe arrhythmia, continuous rapid atrial fibrillation (calm state average ventricular rate > 100 times/min), atrial flutter (calm state average ventricular rate > 100 times/min), frequent ventricular premature beats (24 hours of premature ventricular beats > 7200 times) or ventricular tachycardia; 5. patients with severe primary diseases such as brain, liver, kidney and hematopoietic system; 6. Diabetic patients with unstable blood glucose control and diabetic ketoacidosis; 7. Patients with severe mental illness, such as hallucinations, delusions, panic attacks and suicidal behavior; 8. Women who are pregnant or breast-feeding, and men and women of childbearing age who have recently had family planning; 9. Patients with allergic constitution who are allergic to the tested drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score on the GAD7 Anxiety screening scale;Hamilton Anxiety Scale (HAMA) score;Hamilton Depression Scale (HAMD) score;gallbladder contraction;Corticotropin; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood pressure;Blood pressure variability;Integral of TCM syndrome curative effect;Sleep Status Self-rating scale;Plasma serotonin;glutamate; | — |
Countries
China
Contacts
Public ContactTao Liyu
Shuguang Hospital affiliated to Shanghai University of Traditional Chinese Medicine?
Outcome results
None listed