Study on the technique and curative effect of ultrasound three-dimensional reconstruction guided knee nerve radiofrequency treatment of knee osteoarthritis

Research on new technology and curative effect of knee osteoarthritis based on dual intervention of peripheral and central

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000037294

Enrollment

Unknown

Registered

2020-08-27

Start date

2020-10-01

Completion date

Unknown

Last updated

2020-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Conventional ultrasound guided treatment group:Conventional ultrasound guided

Ultrasound three-dimensional software system guided treatment group:Ultrasound three-dimensional software system guided

Ultrasound three-dimensional software system guidance + repetitive transcranial magnetic stimulation dual treatment group:Ultrasound three-dimensional software system guidance + repetitive transcrania

Conventional ultrasound guided therapy + repetitive transcranial magnetic stimulation dual therapy group:Conventional ultrasound guided therapy + repetitive transcranial magnetic stimulation

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Aged over 60 years; 2) The BMI index is 18.5-24; 3) Meet the diagnostic criteria for knee osteoarthritis (according to the "Guidelines for Diagnosis and Treatment of Osteoarthritis (2018 Edition)" published by the Joint Surgery Group of the Orthopedic Branch of the Chinese Medical Association in the Journal of Chinese Orthopaedics), the diagnosed knee joint Inflammation patients, all patients meet the Kellgren-Lawrence classification II-III KOA imaging diagnostic criteria; 4) VAS score of patients with knee osteoarthritis > 4 points; 5) Obtain the informed consent of the patient, have good compliance, and can cooperate to complete the research.

Exclusion criteria

Exclusion criteria: 1) History of knee surgery or trauma history such as fractures and other traumatic clinical studies; 2) Malnutrition or obesity; 3) Patients with underlying diseases; 4) Patients with neuromuscular diseases are paralyzed or disabled in lower limbs; 5) Suffer from rheumatism, rheumatoid arthritis, joint tuberculosis, bone tumor or vascular disease around the knee joint; 6) Patients with mental illness or with history of epilepsy, persons with severe cognitive impairment and any other diseases or physiological conditions that interfere with the test results. 7) Patients with metal-containing devices such as cochlear implants and pacemakers; 8) The patient is in the active phase of bleeding disease or bleeding tendency; 9) Patients with advanced malignant tumors.

Design outcomes

Primary

Measure	Time frame
Visual Analogue Scale;WOMAC score;	—

Countries

China

Contacts

Public ContactYongjun Zheng

Huadong Hospital Affiliated to Fudan University

zhengyongjun1971@126.com+86 18116267895

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026